第四十五条 旅馆、饭店、影剧院、娱乐场、体育场馆、展览馆或者其他供社会公众活动的场所违反安全规定，致使该场所有发生安全事故危险，经公安机关责令改正而拒不改正的，对其直接负责的主管人员和其他直接责任人员处五日以下拘留；情节较重的，处五日以上十日以下拘留。
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This was not the first time that microbiologists experienced problems with agar. A phenomenon called “The Great Plate Count Anomaly” baffled researchers in the early 20th century when they observed that the number of cells seen under a microscope didn’t match the actual number of colonies growing on an agar plate. Investigating this discrepancy, researchers found agar itself to be the culprit: when nutrient broths are heated with agar during boiling, harmful byproducts (hydroperoxide) can form due to the reaction of agar with phosphate minerals contained in the media. Researchers can avoid this by autoclaving agar separately from the nutrient broth, or by reducing the amount of agar used.
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Scan the crate to find areas of algorithmic weaknesses in extreme cases, and write a sentence for each describing the problem, the potential solution, and quantifying the impact of the solution